Santa Cruz Hotels - Puerto Ayora

Not surprisingly, the largest town in Galapagos also has the most options. There are many choices: the most expensive hotels are on the waterfront or up in the highlands, while the inexpensive choices are set a couple streets back from the water.

Puerto Ayora is probably the best place to stay, as it's centrally located, has a number of restaurants, is known for good dive shops, and is close to several visitor sites like Los Gemelos that don't even require leaving the island!